反応 #10916

反応方程式

cyanamide

1-(4-isothiocyanatophenyl)-4-methylpiperazine

2-bromo-1-(3-difluoromethoxy-phenyl)ethanone

2-Bromo-1-(3-difluoromethoxy-phenyl)ethanone

→

{4-Amino-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-difluoromethoxy-phenyl)-methanone

反応条件

実験手順

This compound was prepared from cyanamide, 1-(4-isothiocyanatophenyl)-4-methylpiperazine (of Example 1) and 2-bromo-1-(3-difluoromethoxy-phenyl)ethanone (of Example 14L) following the procedure used in Example 24. Mass spectrum (ES) MH+=460.

出典