反応 #1080232

反応方程式

3-(4-Methoxyphenyl)propionic acid

thionyl chloride

→

product

3-(4-Methoxyphenyl)propionyl Chloride

溶媒

toluene

反応条件

後処理

1. 1
   その他The solvent is evaporated off under reduced pressure
2. 2
   workup.DISSOLUTIONthe residue is redissolved in toluene
3. 3
   濃縮concentrated to dryness

実験手順

To a suspension of 3-(4-Methoxyphenyl)propionic acid (10 g) in 150 ml of toluene are added 8 ml of thionyl chloride and the mixture is heated to 65° C. for 4 hours. The solvent is evaporated off under reduced pressure and the residue is redissolved in toluene and concentrated to dryness. Such steo is repeated twice. 11 g of the product are obtained as a yellow oil.

出典