反応 #10741

反応方程式

2,4-dimethoxy-5-(thiophen-2-yl)-benzaldehyde

2-acetylbenzoic acid

→

title compound

収率 47.0%

2-[3E-(2,4-Dimethoxy-5-thiophen-2-yl-phenyl)-acryloyl]-benzoic acid

収率 47.0%

反応条件

実験手順

The title compound was prepared by condensing 2,4-dimethoxy-5-(thiophen-2-yl)-benzaldehyde (Ex-6A) and 2-acetylbenzoic acid in a similar manner as described in Ex-3. Yellow solid, 47% yield, mp 196–198° C. 1H-NMR (DMSO-d6) δ 8.00 (s, 1H), 7.84 (d, 1H), 7.61 (m, 3H), 7.45 (m, 3H), 7.21 (d, 1H), 7.08 (t, 1H), 6.75 (s, 1H), 3.95 (s, 3H), 3.86 (s, 3H). MS m/z=394 ([M]+, 100%). Anal. calculated for C22H18O5S: C, 66.99; H, 4.60; S, 8.13. found C, 67.08; H, 4.17; S, 7.97.

出典