反応 #10735

反応方程式

2-hydroxy-4-methoxy-5-thiophen-2-yl-benzaldehyde

chloromethyl-cyclopropane

→

2-Cyclopropylmethoxy-4-methoxy-5-thiophen-2-yl-benzaldehyde

収率 18.0%

反応条件

実験手順

Ex-32A: 2-Cyclopropylmethoxy-4-methoxy-5-thiophen-2-yl-benzaldehyde was prepared in a similar manner as described in Ex-29C from 2-hydroxy-4-methoxy-5-thiophen-2-yl-benzaldehyde (Ex. 29B) and chloromethyl-cyclopropane, 18% yield. 1H-NMR (CDCl3) δ 10.41 (s, 1H), 8.24 (s, 1H), 7.43 (d, 1H), 7.29 (d, 1H), 7.06 (t, 1H), 6.45 (s, 1H), 3.95 (m, 5H), 1.31 (m, 1H), 0.68 (m, 2H), 0.40 (q, 2H).

出典