反応 #1069765

反応方程式

Na2CO3

2-hydrazinopyridine

benzoylacetonitrile

→

1-pyridyl-3-phenyl-5-aminopyrazole

収率 80.5%

溶媒

hydrochloric acid

反応条件

後処理

1. 1
   温度The mixture was refluxed for 3 hrs
2. 2
   温度After cooling
3. 3
   ろ過The yellow precipitate was filtrated
4. 4
   洗浄washed with H2O
5. 5
   その他dried

実験手順

To a solution of 1.09 g 2-hydrazinopyridine in 10 ml 5N hydrochloric acid was added 1.45 g benzoylacetonitrile (from Example 2) under stirring. The mixture was refluxed for 3 hrs. After cooling, the solution was neutralized with Na2CO3. The yellow precipitate was filtrated, washed with H2O, and dried to get 1.9 g 1-pyridyl-3-phenyl-5-aminopyrazole.

出典