反応 #1069480

反応方程式

product

2-(Aminosulfonyl)-N-methoxybenzenecarboximidoyl chloride

phenyl (4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamate

DBU

→

subject compound

収率 67.4%

N-Methoxy-2-[[[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl]amino]sulfonyl]benzenecarboximidoyl chloride

収率 67.4%

反応条件

後処理

1. 1
   ろ過without prior filtration
2. 2
   ろ過with concentrated hydrochloric acid and filtered
3. 3
   洗浄The residue was washed with excess water
4. 4
   その他suction-dried

実験手順

By the procedure of Example 5, 0.4 g of the product of Example 4 was reacted with 0.46 g of phenyl (4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamate and 0.25 g of DBU. The resulting suspension was acidified, without prior filtration, with concentrated hydrochloric acid and filtered. The residue was washed with excess water and suction-dried to yield 0.45 g of the subject compound, m.p. 182° to 184° C.

出典