反応 #1062922

反応方程式

4-(4-propylphenyl)-phenylcyclohexane

cyclohexane

toluene

formic acid

→

3-(4-(4-(4-propylphenyl)phenyl)cyclohexyl)propanal

反応条件

後処理

1. 1
   温度heating the mixture
2. 2
   温度under reflux for 5 hours
3. 3
   洗浄washing the reaction mixture with water after completion of the stirring
4. 4
   乾燥drying over anhydrous magnesium sulfate
5. 5
   濃縮concentrating under reduced pressure
6. 6
   その他isolating the resulting yellow oil

実験手順

This cyclohexane derivative (11.8 g, 30 mmols) was dissolved in toluene (100 ml), followed by adding formic acid (5 ml), heating the mixture under reflux for 5 hours, washing the reaction mixture with water after completion of the stirring, drying over anhydrous magnesium sulfate, concentrating under reduced pressure and isolating the resulting yellow oil, to obtain 3-(4-(4-(4-propylphenyl)phenyl)cyclohexyl)propanal. This product is used in the subsequent reaction without any purification.

出典