反応 #1061098

反応方程式

2-amino-4-chlorobenzonitrile

acetic anhydride

→

2-acetylamino-4-chlorobenzonitrile

溶媒

acetonitrile

反応条件

後処理

1. 1
   温度by heating
2. 2
   その他After the completion of the reaction
3. 3
   workup.DISTILLATIONthe solvent was distilled off
4. 4
   workup.ADDITIONto the residue was added 500 ml of water
5. 5
   ろ過the crystals thus-deposited were collected by filtration
6. 6
   洗浄washed with water
7. 7
   その他dried

実験手順

To 100 ml of acetonitrile were added 30 g of 2-amino-4-chlorobenzonitrile obtained in Step (2) and then 30 ml of acetic anhydride, and the mixture was refluxed by heating. After the completion of the reaction, the solvent was distilled off, then to the residue was added 500 ml of water, and the crystals thus-deposited were collected by filtration, washed with water and dried. Yield: 29 g (75.6%).

出典