反応 #1057984

反応方程式

4-Chloromethylbenzoic acid

borane THF

→

4-chloromethylbenzyl alcohol

収率 79.8%

4-Chloromethylbenzyl alcohol

収率 79.8%

溶媒

THF

反応条件

後処理

1. 1
   その他quenched with excess methanol
2. 2
   その他Evaporation

実験手順

4-Chloromethylbenzoic acid (20 mmol) was dissolved in 20 ml THF, then 30 ml borane/THF were added. The mixture was stirred for 16 hrs at room temperature, and then quenched with excess methanol. Evaporation yielded about 2.5 g 4-chloromethylbenzyl alcohol 36.

出典