反応 #1052049

反応方程式

Tetrafluorophthalic anhydride

N,N-dimethylformamide

pyridine

hydrazine

→

Compound 43

収率 87.0%

tetrafluorophthalhydrazide

収率 87.0%

反応条件

後処理

1. 1
   濃縮The reaction mixture is concentrated in vacuo
2. 2
   workup.ADDITIONthe residue is poured into water (200 mL)
3. 3
   その他The precipitate formed
4. 4
   ろ過is collected by filtration
5. 5
   洗浄washed with water
6. 6
   その他air-dried

実験手順

Tetrafluorophthalic anhydride (400 mg, 1.8 mmol) is dissolved in 10 mL of anhydrous N,N-dimethylformamide (DMF) that contains anhydrous pyridine (0.47 mL, 5.8 mmol). To the solution is slowly added hydrazine (64 mg, 2.0 mmol). The resulting mixture is stirred overnight. The reaction mixture is concentrated in vacuo, and the residue is poured into water (200 mL). The precipitate formed is collected by filtration, washed with water and air-dried to give Compound 43 (369 mg, yield: 87%).

出典