反応 #1036
ord-785f3c16cc454b2f8882766f14740ddd
反応方程式
1-chloro-1,2-dibromotrifluoroethane
1,1,2-trichlorotrifiuoroethane
vinylidene chloride
persulfate sodium formate
→
4-bromo-3-chloro-3,4,4-trifiuorobutanoic acid
3,4- dichloro-3,4,4-trifluorobutanoic acid
反応物
試薬
なし
溶媒
反応条件
詳細条件
See reaction.notes.procedure_details.
実験手順
A one pot reaction of 1-chloro-1,2-dibromotrifluoroethane (VI) or 1,1,2-trichlorotrifiuoroethane (X) with vinylidene chloride in the presence of ammoninm persulfate/sodium formate/air in DMF to give 4-bromo-3-chloro-3,4,4-trifiuorobutanoic acid (VIII) or 3,4- dichloro-3,4,4-trifluorobutanoic acid (XI).