反応 #10341

反応方程式

ethyl-sulfamic acid amide

4,6-dichloro-5-(o-methoxyphenoxy)-2-(4-pyridyl)-pyrimidine

→

pyridine-2-sulfamic acid-[6-chloro-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrimidinyl]-amide

収率 100.5%

反応条件

実験手順

According to the procedure described in referential Example 1e), ethyl-sulfamic acid amide (40 mg, Referential Example 22) was reacted with 4,6-dichloro-5-(o-methoxyphenoxy)-2-(4-pyridyl)-pyrimidine (100 mg, Referential Example 1d)) to give pyridine-2-sulfamic acid-[6-chloro-5-(o-methoxyphenoxy)-2-(4-pyridyl)-4-pyrimidinyl]-amide (70 mg). tR=4.40 min (LC); [M−H]+=434.28 (ES−);

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