反応 #1005986

反応方程式

phenol

4-bromo-2-cyclohex-2-enyl-phenol

MCPBA

→

8-bromo-1,2,3,4-tetrahydro-dibenzofuran-4-ol

溶媒

benzene

反応条件

後処理

1. 1
   その他A solid is precipitated out
2. 2
   ろ過filtered
3. 3
   濃縮The filtrate is concentrated under vacuum
4. 4
   その他chromatographed (10% EtOAc in hexanes)

実験手順

A solution of the phenol and MCPBA in benzene is refluxed overnight. A solid is precipitated out and filtered. The filtrate is concentrated under vacuum and chromatographed (10% EtOAc in hexanes) to give 8-bromo-1,2,3,4-tetrahydro-dibenzofuran-4-ol 108 as clear oil, 0.66 g, 39%.

出典