反応 #1005971

反応方程式

2′-ethylsulfonylacetophenone

phenyltrimethylammonium tribromide

sodium thiosulfate

→

2-bromo-2′-ethylsulfonylacetophenone

収率 164.0%

溶媒

THF

反応条件

後処理

1. 1
   抽出the mixture was extracted with t-butyl methyl ether
2. 2
   洗浄The organic layer was washed with water
3. 3
   乾燥dried over anhydrous magnesium sulfate
4. 4
   濃縮concentrated under reduced pressure

実験手順

A mixture of 1.0 g of 2′-ethylsulfonylacetophenone, 1.86 g of phenyltrimethylammonium tribromide and 10 ml of THF was stirred at room temperature for 3 hours. A 10% aqueous sodium thiosulfate solution was poured to the reaction mixture, and the mixture was extracted with t-butyl methyl ether. The organic layer was washed with water and dried over anhydrous magnesium sulfate, then concentrated under reduced pressure to obtain 1.37 g of 2-bromo-2′-ethylsulfonylacetophenone.

出典