反応 #1005959

反応方程式

(2-ethylsulfanylphenyl) (2-nitro-4-trifluoromethylbenzylidene)amine

triethyl phosphite

→

2-(2-ethylsulfanylphenyl)-6-trifluoromethyl-2H-indazole

収率 78.9%

反応条件

後処理

1. 1
   濃縮concentrated under reduced pressure

実験手順

A mixture of 777 mg of (2-ethylsulfanylphenyl) (2-nitro-4-trifluoromethylbenzylidene)amine and 3 ml of triethyl phosphite was stirred at 100° C. for 15 minutes and then concentrated under reduced pressure. The resulting residue was applied to a silica gel column chromatography to obtain 558 mg of 2-(2-ethylsulfanylphenyl)-6-trifluoromethyl-2H-indazole (hereinafter, referred to as Compound of Present Invention 1).

出典