#NCC(F)F

CCOC(=O)c1sc(N2CC[C@H](NC(=O)c3nc(Cl)c(CC)[nH]3)[C@H](OCC)C2)nc1C(=O)NCC(F)F
Reaction #72233
title compound
収率 79.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_09
O=[N+]([O-])c1ccccc1NCC(F)F
Reaction #163540
N-(2,2-difluoroethyl)-2-nitroaniline
収率 95.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC(F)F)cn1
Reaction #170305
title compound
収率 80.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_09
Fc1cc(CNCC(F)F)cnc1Cl
Reaction #182284
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
FC(F)CNCc1ccc(Cl)nc1
Reaction #192867
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
O=[N+]([O-])c1ccccc1NCC(F)F
Reaction #248027
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
CC(C)(C)OC(=O)N1CCCCC1
Reaction #290272
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
CC(C)c1nc(-c2ccc(F)c(NS(=O)(=O)c3c(F)cccc3F)c2)c(-c2ccnc(NCC(F)F)n2)s1
Reaction #326608
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_02
C[C@@H]1CN(c2c(CO)cc3c(C(=O)NCC(F)F)noc3c2F)C[C@H](C)O1
Reaction #332676
N-(2,2-difluoroethyl)-6-((2R,6S)-2,6-dimethylmorpholino)-7-fluoro-5-(hydroxymethyl)benzo[d]isoxazole-3-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_02
N#Cc1c(NCC(F)F)nc(SCc2csc(-c3ccc(Cl)cc3)n2)c(C#N)c1-c1ccc(OCCO)cc1
Reaction #377651
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
CC1COCCN1c1nc(-c2ccc(NC(=O)NCC(F)F)cc2)nc2c1CCN(c1ncccn1)C2
Reaction #391698
DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
O=[N+]([O-])c1cc2n(n1)CCN(CC(F)F)C2
Reaction #494913
135a
収率 80.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_06
FC(F)CNCc1ccc(Cl)nc1
Reaction #512929
N-[(6-chloropyridin-3-yl)methyl]-2,2-difluoroethane-1-amine
収率 53.9%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2012_01
O=C(N[C@H]1CC[C@H](C(F)(F)F)CC1)c1cc([N+](=O)[O-])c(NCC(F)F)nc1OCC(F)F
Reaction #537529
N-(trans-4-Trifluoromethyl-cyclohexyl)-6-(2,2-difluoroethylamino)-5-nitro-2-(2,2-difluoroethoxy)-nicotinic acid amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_07
CCOC(=O)CC=C(CCl)NCC(F)F
Reaction #538519
ethyl 4-chloro-3-(2,2-difluoroethylamino)but-2-enecarboxylate
収率 98.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_07
CC(C)(C)OC(=O)N1CCOc2ccc(-c3ccc(C(=O)NCC(F)F)cc3)cc2C1
Reaction #561105
1,1-dimethylethyl 7-(4-{[(2,2-difluoroethyl)amino]carbonyl}phenyl)-2,3-dihydro-1,4-benzoxazepine-4 (5H)-carboxylate
収率 85.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2014_01
CCn1c(C(=O)NC(c2ccc(F)c(C(F)(F)F)c2)C(F)(F)F)cc2cc(C(=O)NCC(F)F)c(Cl)cc21
Reaction #601428
6-chloro-N5-(2,2-difluoroethyl)-1-ethyl-N2-{2,2,2-trifluoro-1-[4-fluoro-3-(trifluoromethyl)phenyl]ethyl}-1H-indole-2,5-dicarboxamide
収率 81.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_08
O=C(NCC(F)F)c1cc(F)c(Cl)cc1F
Reaction #658718
desired product
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_05
C[C@@H]1CN(c2c(CO)cc3c(C(=O)NCC(F)F)noc3c2F)C[C@H](C)O1
Reaction #665134
N-(2,2-difluoroethyl)-6-((2R,6S)-2,6-dimethylmorpholino)-7-fluoro-5-(hydroxymethyl)benzo[d]isoxazole-3-carboxamide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_05
CC(C)c1nc(-c2ccc(F)c(NS(=O)(=O)c3c(F)cccc3F)c2)c(-c2ccnc(NCC(F)F)n2)s1
Reaction #677380
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_01
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