HOAT

O=C1COc2ccc(Cl)cc2CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](C2CCCCC2)NC(=O)CN1
Reaction #6783
(6R,20aS)-16-chloro-6-cyclohexyl-2,3,6,7,9,10,18,19-octahydro-1H-pyrrolo[1,2-j][1,4,7,10,13] benzoxatetraazacyclohexadecine-5,8,11,20 (12H,20aH)-tetrone
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
COc1ccccc1-c1cn2c(n1)C(CCSC(c1ccccc1)(c1ccccc1)c1ccccc1)N(C(=O)C(CSC(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OC(C)(C)C)CC2
Reaction #6871
foam
収率 97.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C[C@@H](NC(=O)C1(NC(=O)CC(F)(F)F)CC1)c1ccc(-c2cccc(F)c2C(=O)O)cc1
Reaction #10165
3-fluoro-4′-{(1R)-1-[({1-[(3,3,3-trifluoropropanoyl)amino]cyclopropyl}carbonyl)-amino]ethyl}-1,1′-biphenyl-2-carboxylic acid
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C=CCN(C(=O)OCc1ccccc1)c1cnc2n(c1=O)[C@H](C(=O)Nc1ccccc1)CC2
Reaction #11064
18b
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C=CCN(C(=O)OCc1ccccc1)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OCc3ccccc3)cc1)C[C@@]2(C)N=[N+]=[N-]
Reaction #11067
intermediate
収率 90.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)(C)OC(=O)NC(=N)c1ccc(CNC(=O)[C@@H]2CCc3ncc(N(Cc4cccc(C(F)(F)F)c4)C(=O)OCc4ccccc4)c(=O)n32)cc1
Reaction #11083
intermediate 25b
収率 79.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C=CC[C@@H]1C[C@@H](C(=O)NCc2ccc(C(=N)NC(=O)OCc3ccccc3)cc2)n2c1ncc(N(CC=C)C(=O)OCc1ccccc1)c2=O
Reaction #11087
intermediate 28e
収率 20.8%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
O=C(N[C@@H]1Cc2ccccc2NC1=O)c1cc2cc(Cl)ccc2[nH]1
Reaction #11670
title compound
収率 81.2%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
COC(=O)CN1C(=O)[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)Cc2ccccc21
Reaction #11674
title compound
収率 26.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C=CCN1C(=O)[C@@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)Cc2ccccc21
Reaction #11684
title compound
収率 53.7%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
O=C(N[C@H]1COc2ccccc2NC1=O)c1cc2cc(Cl)ccc2[nH]1
Reaction #11687
title compound
収率 88.8%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
O=C(N[C@@H]1Cc2ccccc2CNC1=O)c1cc2cc(Cl)ccc2[nH]1
Reaction #11693
title compound
収率 44.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)(C)OC(=O)N[C@H]1Cc2ccccc2CNC1=O
Reaction #11695
(S)-4-(t-butyloxycarbonylamino)-2,3,4,5-tetrahydro-2-benzazepin-3(1H)-one
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
O=C(N[C@H]1Cc2ccccc2CNC1=O)c1cc2cc(Cl)ccc2[nH]1
Reaction #11697
title compound
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
COC(=O)C[C@H]1c2ccccc2NC(=O)[C@@H]1NC(=O)c1cc2cc(Cl)ccc2[nH]1
Reaction #11700
title compound
収率 56.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CNc1ccc(Oc2ccnc(C(=O)NCCO)c2)cc1[N+](=O)[O-]
Reaction #41790
4-(4-Methylamino-3-nitro-phenoxy)-pyridine-2-carboxylic acid (2-hydroxy-ethyl)-amide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
Cn1c(Nc2ccc(F)cc2)nc2cc(Oc3ccnc(-c4nc5ccccc5[nH]4)c3)ccc21
Reaction #41795
desired product
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
COC(=O)c1ccc(C(=O)N(C)CCN2CCC(OC(=O)Nc3ccccc3-c3ccccc3)CC2)c(OC)c1
Reaction #42142
title intermediate
収率 89.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
Cn1ccc(NC(=O)C(CC2CCOCC2)c2ccc3c(c2)Nc2ccccc2S3(=O)=O)n1
Reaction #43275
2-(5,5-Dioxo-5,10-dihydrophenothiazin-2-yl)-N-(1-methyl-1H-pyrazol-3-yl)-3-(tetrahydropyran-4-yl)propionamide
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
NC(=O)[C@@H]1CN(Cc2ccccc2)CC[C@@H]1O
Reaction #43617
desired compound
収率 109.6%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2010_06
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