N-cyclopropyl-2-(2,5-dichloropyrimidin-4-yl)-1-(ethoxymethyl)-1H-indole-4-carboxamide

CCOCn1c(-c2nc(NC3CCCC3O)ncc2Cl)cc2c(C(=O)NC3CC3)cccc21

Reaction #908527

DOI: 10.1039/C8SC04228DTest data from https://doi.org/10.1039/C8SC04228D

CCOCn1c(-c2nc(N[C@@H]3CCC[C@@H]3O)ncc2Cl)cc2c(C(=O)NC3CC3)cccc21

Reaction #1973921

2-{5-chloro-2-[(1R,2S)-2-hydroxycyclopentylamino]pyrimidin-4-yl}-N-cyclopropyl-1-(ethoxymethyl)-1H-indole-4-carboxamide

収率 60.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_08

CCOCn1c(-c2nc(N[C@@H]3CCC[C@H]3O)ncc2Cl)cc2c(C(=O)NC3CC3)cccc21

Reaction #1973922

2-{5-chloro-2-[(1R,2R)-2-hydroxycyclopentylamino]pyrimidin-4-yl}-N-cyclopropyl-1-(ethoxymethyl)-1H-indole-4-carboxamide

収率 93.6%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_08