Réaction #992694

ord-a701927ba5cc427dafd9dd4a3346d540

Équation de réaction

O=C(O)CO
Glycolic acid
N=C(N)N.O=C(O)O
Guanidine carbonate
O=C=O
carbon dioxide
→
NC(N)=[NH2+].O=C([O-])CO
Guanidinium Glycolate

Réactifs

O=C(O)CO
Glycolic acid
N=C(N)N.O=C(O)O
Guanidine carbonate
O=C=O
carbon dioxide

Réactifs

Aucun

Solvants

O
water

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe water was removed in vacuo
  2. 2
    Températurewith heating to approximately 90° C
  3. 3
    AutreThe product was isolated as a white solid

Mode opératoire

Glycolic acid (3.0 g, 39.45 mmol) was dissolved in 15 ml of distilled water. Guanidine carbonate (3.55 g, 19.72 mmol) was added in portions at room temperature (carbon dioxide gas was evolved) and the reaction was stirred at room temperature for 4 hours. The water was removed in vacuo with heating to approximately 90° C. The product was isolated as a white solid.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US08012277B2uspto-grants-2011_09