Réaction #992690

ord-691bda8024df427ebdc4c7814c53ac21

Équation de réaction

O=C(O)CC(=O)O
Malonic acid
N=C(N)N.O=C(O)O
Guanidine carbonate
O=C=O
carbon dioxide
→
NC(N)=[NH2+].NC(N)=[NH2+].O=C([O-])CC(=O)[O-]
Bis(guanidinium) Malonate

Réactifs

O=C(O)CC(=O)O
Malonic acid
N=C(N)N.O=C(O)O
Guanidine carbonate
O=C=O
carbon dioxide

Réactifs

Aucun

Solvants

O
water

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe water was removed in vacuo
  2. 2
    Températurewith heating to approximately 90° C. for 4 hours
  3. 3
    AutreThe product was isolated as a white solid

Mode opératoire

Malonic acid (1.00 g, 9.61 mmol) was dissolved in 30 ml of distilled water. Guanidine carbonate (1.73 g, 9.61 mmol) was added via syringe at room temperature (carbon dioxide gas was evolved) and the reaction was stirred at room temperature for 24 hours. The water was removed in vacuo with heating to approximately 90° C. for 4 hours. The product was isolated as a white solid.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US08012277B2uspto-grants-2011_09