Réaction #992675

ord-5e992babb9514177bb334f7e36a2c9ad

Équation de réaction

O=C(O)C(=O)O
Oxalic acid
N=C(N)NN.O=C(O)O
Aminoguanidine bicarbonate
N=C(N)N.O=C(O)O
guanidine carbonate
→
NC(N)=[NH2+].NC(N)=[NH2+].O=C([O-])C(=O)[O-]
Guanidinium Oxalate

Réactifs

O=C(O)C(=O)O
Oxalic acid
N=C(N)NN.O=C(O)O
Aminoguanidine bicarbonate
N=C(N)N.O=C(O)O
guanidine carbonate

Réactifs

Aucun

Solvants

O
water

Conditions de réaction

Température
90°CELSIUS
Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    Autreto avoid bubbling over the sides of the beaker due to the evolution of carbon dioxide during the reaction
  2. 2
    workup.STIRRINGThe reaction was stirred at room temperature overnight (approximately 24 hours)
  3. 3
    AutreThe water was removed from the reaction mixture in vacuo
  4. 4
    AutreThe product was recovered as a crystalline white solid

Mode opératoire

Oxalic acid (200.0 g, 2.22 mol) was weighed into a 2-liter beaker with a magnetic stir bar and dissolved in 1500 ml of distilled water. Aminoguanidine bicarbonate (362.8 g, 2.67 mol) and guanidine carbonate (160.1 g, 0.89 mol) were added in portions with stirring as to avoid bubbling over the sides of the beaker due to the evolution of carbon dioxide during the reaction. The reaction was stirred at room temperature overnight (approximately 24 hours). The water was removed from the reaction mixture in vacuo with heating to approximately 90° C. for 4 hours. The product was recovered as a crystalline white solid.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US08012277B2uspto-grants-2011_09