Réaction #955971

Équation de réaction

thiophene-3,4-dicarboxylic anhydride

4-(3-ethylheptyl)-2,3,5,6-tetrafluoroaniline

→

5-(4-(3-ethylheptyl)-2,3,5,6-tetrafluorophenyl)-4H-thieno[3,4-c]pyrrole-4,6(5H)-dione

Solvants

toluene

Conditions de réaction

Traitement

1. 1
   FiltrationThe crude product is collected by filtration of the cold reaction mixture
2. 2
   AutreAnother portion of product can be recovered
3. 3
   Lavageby washing the filtrate with 5% hydrochloric acid
4. 4
   Autreevaporating the solvent
5. 5
   AutreThe target molecule is purified by recrystallization from toluene
6. 6
   workup.DISSOLUTIONdissolved in 150 ml of thionyl chloride
7. 7
   Températurerefluxed for 3 hrs
8. 8
   ConcentrationThe reaction mixture is concentrated down
9. 9
   Autredried
10. 10
    Autrepurified

Mode opératoire

A solution of thiophene-3,4-dicarboxylic anhydride (8.0 mmol) and 4-(3-ethylheptyl)-2,3,5,6-tetrafluoroaniline (8.5 mmol) in 125 ml of toluene is refluxed for 24 h. The crude product is collected by filtration of the cold reaction mixture. Another portion of product can be recovered by washing the filtrate with 5% hydrochloric acid and then evaporating the solvent. The target molecule is purified by recrystallization from toluene, dissolved in 150 ml of thionyl chloride and refluxed for 3 hrs. The reaction mixture is concentrated down, dried, and purified.

Source