Réaction #95250

Équation de réaction

2-(5-carboxypentyl)-2-cyclopentenone

p-toluenesulfonic acid

→

2-(5-carbethoxypentyl)-2-cyclopentenone

Solvants

ethanol

Conditions de réaction

Traitement

1. 1
   AutreThe solvent is evaporated
2. 2
   workup.DISSOLUTIONthe residue is dissolved in ether
3. 3
   LavageThe organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution
4. 4
   Séchagedried (MgSO4)
5. 5
   Autreevaporated
6. 6
   Autreto give 1.371 g

Mode opératoire

A solution of 1.309 g. (0.00668 mole) of 2-(5-carboxypentyl)-2-cyclopentenone (Example 52) and 90 mg. of p-toluenesulfonic acid in 150 ml. of ethanol is refluxed for 18 hours. The solvent is evaporated and the residue is dissolved in ether. The organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution, dried (MgSO4), and evaporated to give 1.371 g. of a light yellow oil.

Source