Réaction #9459

Équation de réaction

4—Chloro-3-nitro-7-phenylquinoline

3-methylsulfanyl-propylamine

→

(3-methylsulfanylpropyl)-(3-nitro-7-phenylquinolin-4-yl)amine

Rendement 93.3%

Conditions de réaction

Traitement

1. 1
   workup.ADDITIONtreated
2. 2
   AutreRecrystallization from isopropanol

Mode opératoire

4—Chloro-3-nitro-7-phenylquinoline (5.3 g, 18.8 mmol) and 3-methylsulfanyl-propylamine (2.17 g, 20.6 mmol) were combined and treated according to the general procedure described in Part E of Example 1. Recrystallization from isopropanol afforded 6.2 g of (3-methylsulfanylpropyl)-(3-nitro-7-phenylquinolin-4-yl)amine as gold plates.

Source