Réaction #94331

ord-177c8f38f14b4e4d99132f91365c0976

Équation de réaction

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O.O.O.O
ampicillin trihydrate
[Na+].[OH-]
sodium hydroxide
[Na+].[OH-]
NaOH
→
CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)[O-].[Na+]
sodium ampicillin

Réactifs

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O.O.O.O
ampicillin trihydrate
[Na+].[OH-]
sodium hydroxide
[Na+].[OH-]
NaOH

Réactifs

Aucun

Solvants

O
water

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

A suspension of 24.18 gm (60 millimols) of ampicillin trihydrate in 140 ml of water was admixed with 55.2 ml of an aqueous 1N sodium hydroxide solution (8% less than equimolar amount of NaOH) in the manner and under the conditions described in Example 1, and the sodium ampicillin was isolated in exactly the same manner as in Example 1.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US04130558uspto-grants-1978_12