Réaction #93929

ord-adfe98a2b78d47d4a79ba1d2b68f4555

Équation de réaction

CCCCC[C@H](O)C#CCC(CCCCCCC(=O)O)S(C)(=O)=O
8-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid
CS(=O)(=O)C(CC#CC1(O)CCCCC1)CCCCCCC(=O)O
8-methylsulfonyl-11-(1-hydroxycyclohexyl)-10-undecynoic acid
→
CS(=O)(=O)C(CCCCCCC(=O)O)CCCC1(O)CCCCC1
8-methylsulfonyl-11-(1-hydroxycyclohexyl)-undecanoic acid

Réactifs

CCCCC[C@H](O)C#CCC(CCCCCCC(=O)O)S(C)(=O)=O
8-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid
CS(=O)(=O)C(CC#CC1(O)CCCCC1)CCCCCCC(=O)O
8-methylsulfonyl-11-(1-hydroxycyclohexyl)-10-undecynoic acid

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe synthesis of this compound

Mode opératoire

The synthesis of this compound is carried out by the hydrogenation process described in Example 15 except that 8-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid is replaced by an equivalent quantity of 8-methylsulfonyl-11-(1-hydroxycyclohexyl)-10-undecynoic acid (Example 19).

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US04128564uspto-grants-1978_12