Réaction #93924

ord-69fe7661c6014a8f8bc7321ce78f170d

Équation de réaction

CCCCCC(CCCC(CCCCCCC(=O)OC)S(C)(=O)=O)OC(C)=O
methyl 8-methylsulfonyl-12-acetoxyheptadecanoate
CCCCC[C@@H](C#CCC(CCCCCCC(=O)OC)S(C)(=O)=O)OC(C)=O
methyl 8-methylsulfonyl-12(S)-acetoxy-10-heptadecynoate
→
CCCCC[C@H](O)C#CCC(CCCCCCC(=O)O)S(C)(=O)=O
8-methylsulfonyl-12(S)-hydroxy-10-heptadecynoic acid

Réactifs

CCCCCC(CCCC(CCCCCCC(=O)OC)S(C)(=O)=O)OC(C)=O
methyl 8-methylsulfonyl-12-acetoxyheptadecanoate
CCCCC[C@@H](C#CCC(CCCCCCC(=O)OC)S(C)(=O)=O)OC(C)=O
methyl 8-methylsulfonyl-12(S)-acetoxy-10-heptadecynoate

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe synthesis of this compound

Mode opératoire

The synthesis of this compound is carried out by the method of Example 3, Step E, except that methyl 8-methylsulfonyl-12-acetoxyheptadecanoate is replaced by an equivalent quantity of methyl 8-methylsulfonyl-12(S)-acetoxy-10-heptadecynoate.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US04128564uspto-grants-1978_12