Réaction #939019

Équation de réaction

6-decenoic acid

Methyl 6-bromodecanoate

quinoline

methyl 5-decenoate

methyl 6-decenoate

→

5-decenoic acid

Rendement 35.0%

Conditions de réaction

Traitement

1. 1
   Autreto react at 240° C. for 5 minutes
2. 2
   Extractionthe reaction solution was extracted with ether
3. 3
   Lavagewashed with dilute sulfuric acid
4. 4
   Lavagewashed with water
5. 5
   Autredried
6. 6
   Autreevaporated
7. 7
   Autreto remove the solvent
8. 8
   workup.DISTILLATIONdistilled
9. 9
   Autregiving

Mode opératoire

Methyl 6-bromodecanoate (1.2 g) and quinoline (1.2g) were mixed together, and then allowed to react at 240° C. for 5 minutes. After the reaction was completed, the reaction solution was extracted with ether, washed with dilute sulfuric acid, washed with water, dried, evaporated to remove the solvent, and then distilled, thereby giving a mixture of methyl 5-decenoate and methyl 6-decenoate (310 mg). The mixture was hydrolyzed in a coventional manner, thereby giving a mixture (270 mg) of 5-decenoic acid and 6-decenoic acid (1/1).

Source