Réaction #933302

ord-a0a7402c577240b392fae355432f714a

Équation de réaction

c1cc(OCC2CO2)ccc1CCOCC1CC1
1-[4-(2-cyclopropylmethoxy-ethyl)phenoxy]-2,3-epoxypropane
NCCOc1ccc(C2=NNC(=O)CC2)cc1
6-[4-(2-aminoethoxy)-phenyl]-4,5-dihydro-3(2H)-pyridazinone
→
O=C1CCC(c2ccc(OCCNCC(O)COc3ccc(CCOCC4CC4)cc3)cc2)=NN1
6-[4-[2-[3-(4-(2-Cyclopropylmethoxy-ethyl)phenoxy)-2-hydroxypropylamino]ethoxy]phenyl]-4,5-dihydro-3(2H)-pyridazinone

Réactifs

c1cc(OCC2CO2)ccc1CCOCC1CC1
1-[4-(2-cyclopropylmethoxy-ethyl)phenoxy]-2,3-epoxypropane
NCCOc1ccc(C2=NNC(=O)CC2)cc1
6-[4-(2-aminoethoxy)-phenyl]-4,5-dihydro-3(2H)-pyridazinone

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Prepared analogously to Example 1 from 1-[4-(2-cyclopropylmethoxy-ethyl)phenoxy]-2,3-epoxypropane and 6-[4-(2-aminoethoxy)-phenyl]-4,5-dihydro-3(2H)-pyridazinone.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05135932uspto-grants-1992_08