Réaction #91215

Équation de réaction

3-Chloromethyl-2-cyclopentylsulfanyl-pyridine

3-(4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester

→

title compound

Rendement 40.0%

3-[4-(2-cyclopentylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-2-methyl-propionic acid

Rendement 40.0%

Conditions de réaction

Traitement

1. 1
   Autreto react sequentially in the same manner as in Steps A and B of Example 1

Mode opératoire

3-Chloromethyl-2-cyclopentylsulfanyl-pyridine (0.056 g, 0.24 mmol) obtained in Step C of Preparation Example 8 and 3-(4-hydroxy-phenyl)-2-methyl-propionic acid ethyl ester obtained in Step B of Preparation Example 3 A were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (0.035 g, 40%).

Source