Réaction #91211

Équation de réaction

3-Chloromethyl-2-cyclopentylsulfanyl-pyridine

4-(4-hydroxy-phenyl)-butyric acid ethyl ester

→

title compound

Rendement 94.0%

4-[4-(2-cyclopentylsulfanyl-pyridin-3-ylmethoxy)-phenyl]-butyric acid

Rendement 94.0%

Conditions de réaction

Traitement

1. 1
   Autreto react sequentially in the same manner as in Steps A and B of Example 1

Mode opératoire

3-Chloromethyl-2-cyclopentylsulfanyl-pyridine (0.020 g, 0.09 mmol) obtained in Step C of Preparation Example 8 and 4-(4-hydroxy-phenyl)-butyric acid ethyl ester (0.018 g, 0.09 mmol) obtained in Step E of Preparation Example 13 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (0.031 g, 94%).

Source