Réaction #89622

ord-031d4fef6cf0407a9a44ce165221682a

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

But-3-yn-2-ol was added into a solution of ethyl magnesium bromide (EtMgBr) in tetrahydrofuran (THF). Hept-4-enal was then dropped into the mixture at room temperature and aged for 2 hours. The rush over process provided the product undec-8-en-3-yne-2,5-diol.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US09441185B2uspto-grants-2016_09