Réaction #84979

Équation de réaction

4-chloro-2-(5-chloro-2-oxo-1,2-dihydropyridin-4-yl)benzonitrile

tert-butyl bromoacetate

→

tert-Butyl [5-chloro-4-(5-chloro-2-cyanophenyl)-2-oxopyridin-1(2H)-yl]acetate

Conditions de réaction

Traitement

1. 1
   Autreaccording to General Method 4B at 100° C

Mode opératoire

400 mg (purity 91%, 1.37 mmol) of 4-chloro-2-(5-chloro-2-oxo-1,2-dihydropyridin-4-yl)benzonitrile and 1.2 eq. of tert-butyl bromoacetate were reacted according to General Method 4B at 100° C. Yield: 421 mg (80% of theory)

Source