Réaction #848

Équation de réaction

p-hydroxybenzoic acid

decanoic acid chloride

pyridine

→

p-decanoyloxybenzoic acid

Solvants

water

Conditions de réaction

Traitement

1. 1
   Extractionan organic layer was extracted with dichloromethane
2. 2
   LavageThe organic layer was washed with 1N hydrochloric acid
3. 3
   Séchagedried over anhydrous sodium sulfate
4. 4
   workup.DISTILLATIONthe solvent was distilled off
5. 5
   Lavageresidue was washed with n-hexane
6. 6
   Autredried
7. 7
   Autreto give a crude end product

Mode opératoire

10 Grams of p-hydroxybenzoic acid and 15 g of decanoic acid chloride were stirred at room temperature, and 7.2 g of pyridine was dropwise added. After the mixture was stirred for 1 day, a reaction product was poured into water, and an organic layer was extracted with dichloromethane. The organic layer was washed with 1N hydrochloric acid and dried over anhydrous sodium sulfate, the solvent was distilled off, and then residue was washed with n-hexane and then dried to give a crude end product.

Source