Réaction #8419

Équation de réaction

4-(4-boc-piperazinyl)-indole

3,4-dimethoxyphenylsulfonyl chloride

→

title compound

1-[(3,4-Dimethoxyphenyl)sulfonyl]-4-(1-piperazinyl)-1H-indole hydrochloride

Conditions de réaction

Mode opératoire

The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 3,4-dimethoxyphenylsulfonyl chloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.00 (br, 1 H), 7.82 (d, J=5 Hz, 1 H), 7.66 (d, J=8 Hz, 1 H), 7.57 (m, 1 H), 7.40 (d, J=3 Hz, 1 H), 7.24 (t, J=8 Hz, 1 H), 7.10 (d, J=8 Hz, 1 H), 6.90 (d, J=5 Hz, 1 H), 6.78 (d, J=8 Hz, 1 H), 3.78 (s, 6 H), 3.24 (m, 8 H); MS (ESI+) for m/z 402 (M+H)+.

Source