Réaction #84061

Équation de réaction

2-chloro-6-methoxyquinoline

Intermediate 1

2-chloro-6-methoxyquinoline

(4-(1H-tetrazol-5-yl)phenyl)boronic acid

→

2-(4-(1H-tetrazol-5-yl)phenyl)quinolin-6-ol

Conditions de réaction

Mode opératoire

Followed Scheme 2, A conditions: Starting materials: 2-chloro-6-methoxyquinoline (Intermediate 1) and (4-(1H-tetrazol-5-yl)phenyl)boronic acid. 1H NMR (DMSO-d6, 400 MHz): δ 10.15 (s, 1H), 8.45 (d, 2H), 8.31-8.28 (d, 1H), 8.22-8.12 (m, 3H), 7.98-7.95 (d, 1H), 7.39-7.35 (dd, 1H), 7.21 (s, 1H). MS (ESI): m/z 290.08 [M+H]+.

Source