Réaction #82230

Équation de réaction

potassium carbonate

5-bromosalicylaldehyde

N,N-dimethylthiocarbamoyl chloride

→

5-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde

Rendement 78.9%

Solvants

acetone

Conditions de réaction

Traitement

1. 1
   AutreThe resulting reaction solution
2. 2
   Autrethus precipitated
3. 3
   Filtrationwere collected by filtration
4. 4
   Autredried

Mode opératoire

8.13 g of 5-bromosalicylaldehyde was dissolved in 100 ml of acetone, followed by the addition of 6.7 g of anhydrous potassium carbonate. With stirring at room temperature, 5.0 g of N,N-dimethylthiocarbamoyl chloride was added to the above solution, and the stirring was continued for two hours. The resulting reaction solution was poured into ice water, and crystals thus precipitated were collected by filtration, and dried to obtain 9.2 g of 5-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde.

Source