Réaction #816381

Équation de réaction

3,6-di(azido)-1,2,4,5-tetrazine

3,6-bis(3,5-dimethylpyrazol-1-yl)-1,2,4,5-tetrazine

NH2NH2.H2O

→

3,6-di(hydrazino)-1,2,4,5-tetrazine

Conditions de réaction

Mode opératoire

The invention also includes a method for preparing 3,6-di(azido)-1,2,4,5-tetrazine. The method involves reacting 3,6-bis(3,5-dimethylpyrazol-1-yl)-1,2,4,5-tetrazine with NH2NH2.H2O to form 3,6-di(hydrazino)-1,2,4,5-tetrazine (DHT), then reacting the 3,6-di(hydrazino)-1,2,4,5-tetrazine with an aqueous hydrochloric acid solution of NaNO2, thereby forming a crude reaction product comprising 3,6-di(azido)-1,2,4,5-tetrazine and solid impurities, and extracting the 3,6-di(azido)-1,2,4,5-tetrazine away from the impurities in the crude reaction product.

Source