Réaction #816380

ord-337954db342c466cbcef6fe9888bb754

Équation de réaction

Cc1c(N=O)c(=O)n(-c2ccccc2)n1C
1,5-dimethyl-4-nitroso-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
Cc1ccc(N)cc1N
4-methylbenzene-1,3-diamine
[Na+].[O-][Cl+3]([O-])([O-])[O-]
Sodium perchlorate
→
CC1=C/C(=N\c2c(C)n(C)n(-c3ccccc3)c2=O)C(N)=CC1=[NH2+].[O-][Cl+3]([O-])([O-])[O-]
(4E)-5-amino-4-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)imino]-2-methylcyclohexa-2,5-dien-1-iminium perchlorate

Réactifs

Cc1c(N=O)c(=O)n(-c2ccccc2)n1C
1,5-dimethyl-4-nitroso-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
Cc1ccc(N)cc1N
4-methylbenzene-1,3-diamine
[Na+].[O-][Cl+3]([O-])([O-])[O-]
Sodium perchlorate

Réactifs

Aucun

Solvants

CC(=O)O
acetic acid
O
water

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    workup.WAITthe mixture was left
  2. 2
    workup.WAITto stand for 30 minutes at zero degrees

Mode opératoire

50 mmol of 1,5-dimethyl-4-nitroso-2-phenyl-1,2-dihydro-3H-pyrazol-3-one was dissolved in a solution of 850 ml of acetic acid and 1250 ml of water. This solution was admixed with 50 mmol of 4-methylbenzene-1,3-diamine and stirring was continued for 2 h 30 min. Sodium perchlorate was added to saturation, and the mixture was left to stand for 30 minutes at zero degrees.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US07582123B2uspto-grants-2009_09