Réaction #814435

ord-4b11baa908ad48bfbe38b8c292d348bb

Équation de réaction

Cc1ncsc1C=O
4-methyl-5-thiazolecarbaldehyde
CN(C)c1cccc(Br)c1
3-bromo-N,N-dimethylaniline
→
Cc1ncsc1C(O)c1cccc(N(C)C)c1
title compound
Cc1ncsc1C(O)c1cccc(N(C)C)c1
1-(3-Dimethylaminophenyl)-1-(4-methyl-5-thiazolyl)methanol

Réactifs

Cc1ncsc1C=O
4-methyl-5-thiazolecarbaldehyde
CN(C)c1cccc(Br)c1
3-bromo-N,N-dimethylaniline

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

The title compound was prepared from 4-methyl-5-thiazolecarbaldehyde and 3-bromo-N,N-dimethylaniline using the method of Example 32. M.p. 135°-138° C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US05712299uspto-grants-1998_01