Réaction #792146

Équation de réaction

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one

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title compound

Rendement 59.6%

1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)propan-1-one

Rendement 59.6%

Solvants

methanol

Conditions de réaction

Traitement

1. 1
   Autreto give a yellow solution
2. 2
   FiltrationThe reaction mixture was filtered
3. 3
   Autreevaporated
4. 4
   Lavagethe solid residue was washed with diethylether
5. 5
   Autredried

Mode opératoire

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one (0.5 g, 1.857 mmol) was added to methanol (50 ml) to give a yellow solution. Palladium on carbon (0.05 g) was added. Product was hydrogenated while stirring till conversion was completed (checked by TLC). The reaction mixture was filtered, evaporated and the solid residue was washed with diethylether, and dried to yield 0.3 g (57%) of the title compound.

Source