Réaction #79153

ord-816abe7237094fe3ac23eee9419270c4

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Free base of the titled compound was prepared from 2-styryl-1H-benzimidazole and 2,6-dichloropyridine according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method B). MW: 331.81; mp: 122.0-123.0° C.; 1H-NMR (DMSO) δ: 8.22 (1H, t, J=7.9 Hz), 7.91 (1H, d, J=16.1 Hz), 7.79-7.72 (3H, m), 7.67-7.63 (2H, m), 7.50-7.47 (1H, m), 746-7.28 (5H, m), 7.23 (1H, d, J=16.1 Hz).

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06713482B2uspto-grants-2004_03