Réaction #78223

ord-f03d6521fe21468caf92eef68013cb3c

Équation de réaction

COC(=O)c1ccc(NC(=N)N)cc1OC.O=C(O)C(F)(F)F
methyl 4-guanidino-2-methoxybenzoate trifluoroacetate
Cl
hydrochloric acid
→
COc1cc(NC(=N)N)ccc1C(=O)O.Cl
title compound
COc1cc(NC(=N)N)ccc1C(=O)O.Cl
4-Guanidino-2-methoxybenzoic acid hydrochloride

Réactifs

COC(=O)c1ccc(NC(=N)N)cc1OC.O=C(O)C(F)(F)F
methyl 4-guanidino-2-methoxybenzoate trifluoroacetate
Cl
hydrochloric acid

Réactifs

Aucun

Conditions de réaction

Température
80°CELSIUS
Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe solvent was evaporated

Mode opératoire

384 mg of methyl 4-guanidino-2-methoxybenzoate trifluoroacetate was dissolved in 8 ml of 3 M hydrochloric acid, and they were stirred at 80° C. for 2.5 hours. The solvent was evaporated to obtain the title compound.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06710056B2uspto-grants-2004_03