Réaction #7656

Équation de réaction

6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one

1-adamantanecarbonyl chloride

→

N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]-1-adamantanecarboxamide

Conditions de réaction

Traitement

1. 1
   AutreThe crude product is used in the next step without further purification

Mode opératoire

In analogy to the procedure for Example 36A, 150 mg (0.67 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 150 mg (0.74 mmol) 1-adamantanecarbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.

Source