Réaction #7651

Équation de réaction

6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one

bicyclo[2.2.1]hept-2-ylacetyl chloride

→

2-Bicyclo[2.2.1]hept-2-yl-N-[1-(3-cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]acetamide

Conditions de réaction

Traitement

1. 1
   AutreThe crude product is used in the next step without further purification

Mode opératoire

In analogy to the procedure for Example 36A, 150 mg (0.67 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 130 mg (0.74 mmol) bicyclo[2.2.1]hept-2-ylacetyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.

Source