Réaction #75698

ord-f65ef558ff1b43d8b187200c04483bf7

Équation de réaction

Nc1ccc(OC(F)(F)F)cc1
4-(trifluoromethoxy)-aniline
CCOC(=O)C=O
glyoxylic acid ethyl ester
C1=CCCCCCC1
cyclooctene
→
CCOC(=O)C1Nc2ccc(OC(F)(F)F)cc2C2CCCCCCC12
Compound 76
CCOC(=O)C1Nc2ccc(OC(F)(F)F)cc2C2CCCCCCC12
2-trifluoromethoxy-5,6,6a,7,8,9,10,11,12,12a-decahydro-5-aza-cycloocta-[a]naphthalene-6-carboxylic Acid Ethyl Ester

Réactifs

Nc1ccc(OC(F)(F)F)cc1
4-(trifluoromethoxy)-aniline
CCOC(=O)C=O
glyoxylic acid ethyl ester
C1=CCCCCCC1
cyclooctene

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

Compound 76 was prepared from 4-(trifluoromethoxy)-aniline, glyoxylic acid ethyl ester and cyclooctene by the automated process.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06699877B2uspto-grants-2004_03