Réaction #75688

Équation de réaction

4-chloroaniline

ethylglyoxalate

4-bromostyrene

trifluoroacetic acid

→

Compound 56

6-chloro-4-(4-bromophenyl)-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid Ethyl Ester

Solvants

acetonitrile

Conditions de réaction

Mode opératoire

Compound 56 was prepared by the basic process from 5.0 mmol 4-chloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 4-bromostyrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

Source