Réaction #75671

Équation de réaction

3,5-dichloroaniline

ethylglyoxalate

4-bromostyrene

trifluoroacetic acid

→

Compound 39

4-(4-bromophenyl)-5,7-dichloro-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid Ethyl Ester

Solvants

acetonitrile

Conditions de réaction

Mode opératoire

Compound 39 was prepared by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 4-bromostyrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

Source