Réaction #75646

Équation de réaction

3,5-dichloroaniline

ethylglyoxalate

1,2-Dihydronaphthalene

trifluoroacetic acid

→

Compound 12

Rendement 85.0%

1,3-dichloro-5,6,6a,7,8,12b-hexahydrobenzo[k]phenanthridine-6-carboxylic Acid Ethyl Ester

Rendement 85.0%

Solvants

acetonitrile

Conditions de réaction

Mode opératoire

Compound 12 was prepared in a yield of 85% by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 1,2-Dihydronaphthalene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

Source