Réaction #75438

Équation de réaction

5-methyl-4-hexenoic acid

diazomethane

→

title product

Methyl 5-methyl-4-hexenoate

Solvants

ether

ether

Conditions de réaction

Traitement

1. 1
   AutreThe solvent was then evaporated under vacuum

Mode opératoire

Freshly prepared diazomethane in ether was added to an ice-cooled solution of 5-methyl-4-hexenoic acid (4.5 g, 35.16 mmol) in ether (10 mL) until the solution became slightly yellow in color. The solvent was then evaporated under vacuum to afford the title product as a colorless liquid in near quantitative yield (4.90 g). This product was used in the next reaction step without further purification. 1H NMR (CDCl3) δ1.62 & 1.68[2s, 6H, C(CH3)2], 2.30[m, 4H, (CH2)2], 3.69(s, 3H, COOCH3) and 5.07(t, 1H, CH).

Source